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Freud's commendation of cocaine as a cure for morphine addiction has not been widely echoed in recent years.
Of these possibilities, the simultaneous use of opioids and cocaine has been commonly reported. Cocaine enhances the analgesic effect of morphine40 and
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Cocaine was driven underground in 1914 by the Harrison Tax Act, which mistakenly classified it as a narcotic, subject to the same penalties as opium, morphine,
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In this study opiates (morphine and codeine) and cocaine and its related metabolites (benzoylecgonine and cocaethylene) were analyzed in pericardial fluid by
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The results obtained by any of the methods used reflect a chemical interaction between cocaine and morphine, but not between cocaine and heroin.
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Bhat R. Prenatal cocaine and morphine alter brain cyclin-dependent kinase 5 ( Cdk5) activity in rat pups. Neurotoxicol Teratol 28:625 (2006)
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We recently demonstrated that combining cocaine and morphine could enhance their reinforcing effects which may be mediated by the dopaminergic system.
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These were cases in which morphine had also been freely used. In the cases in which I gradually reduced the dose of cocaine, morphine had not been
N2O did not induce CPP but impaired the acquisition of morphine-induced CPP and blocked the expression of cocaine- and morphine-
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We have tested the effect of alkaloids (cocaine, morphine) and enkephalins on neutral Our findings suggested that the drugs of abuse, cocaine and morphine,
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His subsequent efforts to rid himself of the dependence led Dr. Halsted to "cure" his cocaine habit by switching to morphine injections. At one time, his habit was
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Both cocaine and morphine significantly increased rates of responding. Naltrindole (NTI; 10 mg/kg) reduced rats' rates of responding under cocaine to those
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Sir William revealed that Halsted had cured his cocaine habit by turning to morphine. Thus Halsted was a morphine addict at the age of thirty-four, when Welch
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Cocaine was also used in medicine: in 1879 to treat morphine addiction, and in 1884 as a local anaesthetic. Around this time Sigmund Freud published his work
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An evaluation of the analgesic, mood and side effects of the combination of intramuscular morphine and oral cocaine was conducted in 17 patients with
Morphine, for example, was first synthesized in 1803, cocaine in 1859. Still, even allowing for some exaggeration on the part of historians, you have to think the
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Amounts of cocaine, benzoylecgonine (cocaine metabolite), codeine, and morphine in a hair standard reference material were determined by
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Acronym Finder: HMC stands for Heroin, Morphine, and Cocaine mixture. This definition appears very rarely.
addictive drugs, such as cocaine, morphine, nicotine, ethanol and amphetamines , induce long-term synaptic plasticity in neurons of the brain's reward system.
Both cocaine and morphine significantly increased rates of responding. Naltrindole (NTI; 10 mg/kg) reduced rats' rates of responding under cocaine to
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Coca was later introduced to Europe, where the alkaloid cocaine was isolated. Its medicinal effects on depression, alcohol and morphine addiction, fatigue, and
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